I am a postdoctoral researcher in the Infectious Disease Dynamics Group at Johns Hopkins Bloomberg School of Public Health. My current research focuses on estimating the burden and distribution of cholera in Bangladesh based on serological biomarkers. As a side project, I have estimated some of the epidemiological parameters of the recent 2019-nCoV outbreak.
During my PhD at UMass, I worked with the Thailand Ministry of Public Health to forecast dengue fever incidence at short and long time scales. During my time as a grad student, I developed a number of Shiny web applications for various projects (SEIGMA, dengue predictions, and ALERT).
Outside of the office, my interests include sports, travel, economics, voting reform, transportation issues, and video games. Check out my full bio for more details!
PhD in Biostatistics, 2019
University of Massachusetts, Amherst
MS in Biostatistics, 2014
University of Massachusetts, Amherst
BS in Business, Operations Management, 2009
University of Maryland, College Park
A novel human coronavirus (2019-nCoV) was identified in China in December, 2019. There is limited support for many of its key epidemiologic features, including the incubation period, which has important implications for surveillance and control activities. Here, we use data from public reports of 101 confirmed cases in 38 provinces, regions, and countries outside of Wuhan (Hubei province, China) with identifiable exposure windows and known dates of symptom onset to estimate the incubation period of 2019-nCoV. We estimate the median incubation period of 2019-nCoV to be 5.2 days (95% CI 4.4, 6.0), and 97.5% of those who develop symptoms will do so within 10.5 days (95% CI 7.3, 15.3) of infection. These estimates imply that, under conservative assumptions, 64 out of every 10,000 cases will develop symptoms after 14 days of active monitoring or quarantine. Whether this risk is acceptable depends on the underlying risk of infection and consequences of missed cases. The estimates presented here can be used to inform policy in multiple contexts based on these judgments.
Dengue hemorrhagic fever (DHF), a severe manifestation of dengue viral infection that can cause severe bleeding, organ impairment, and even death, affects between 15,000 and 105,000 people each year in Thailand. While all Thai provinces experience at least one DHF case most years, the distribution of cases shifts regionally from year to year. Accurately forecasting where DHF outbreaks occur before the dengue season could help public health officials prioritize public health activities. We develop statistical models that use biologically plausible covariates, observed by April each year, to forecast the cumulative DHF incidence for the remainder of the year. We perform cross-validation during the training phase (2000–2009) to select the covariates for these models. A parsimonious model based on preseason incidence outperforms the 10-y median for 65% of province-level annual forecasts, reduces the mean absolute error by 19%, and successfully forecasts outbreaks (area under the receiver operating characteristic curve = 0.84) over the testing period (2010–2014). We find that functions of past incidence contribute most strongly to model performance, whereas the importance of environmental covariates varies regionally. This work illustrates that accurate forecasts of dengue risk are possible in a policy-relevant timeframe.